Malignant fibrous histiocytoma at the site of hip replacement in association with chronic infection

Orthop Rev 1994 May;23(5):427-32
Aboulafia AJ, Littelton K, Shmookler B, Malawer MM.

A case of malignant fibrous histiocytoma that developed at the site of an infected metallic implant is presented. The total hip endoprosthesis was composed of a cobalt-chromium alloy. There was a relatively short latency period (less than 2 years) between the initial surgery and the development of malignancy in this patient. The authors urge development of a tumor registry to discover if the association between hip replacement and malignancy is coincidental. 

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